The Cade R. Alpard Foundation
for Pediatric Liver Disease
Cade's Foundation is dedicated to improving the lives of children with liver disease
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RETURN ON INVESTMENT - PRODUCTIVITY
The return on investment for Cade's Foundation is that research efforts we support lead to further grant funding, investigator recognition/awards, publications, and ideally clinically impacting children with liver disease.
Project: Potential Screening Test for Biliary Atresia
Investigator: Sanjiv Harpavat, M.D., Ph.D.
ROI:
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2015 BCM Pilot Award from the Caroline Wiess Law Fund for Research in Molecular Medicine
($30K/yr - 1 year)
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2015 AASLD Jan Albrecht Clinical and Translational Research Award in Liver Disease
($75K/yr - 2 years)
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NIH K23 Training Grant
($150K/yr - 5 years)
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TCH GI Pilot Grant
($15K/yr - 1 year)
Publications:
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Simple Blood Test Developed to Screen for Life Threatening Liver Disease
click on pdf for NEJM article (Aug. 11, 2016)
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P2X3 purinergic receptor overexpression is associated with poor recurrence-free survival in hepatocellular carcinoma patients
click on pdf for Oncotarget article (December 2015)
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P2Y2 purinergic receptor activation is essential for efficient hepatocyte proliferation in response to partial hepatectomy
click on pdf for Am J Physiol Gastrointest Liver Physiol article (December 2014)
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Cardiomyopathy reverses with recovery of liver injury, cholestasis and cholanemia in mouse model of biliary fibrosis
click on pdf for Liver International article (April 2015)
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