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The return on investment for Cade's Foundation is that research efforts we support lead to further grant funding, investigator recognition/awards, publications, and ideally clinically impacting children with liver disease.

Project:  Potential Screening Test for Biliary Atresia

Investigator:  Sanjiv Harpavat, M.D., Ph.D.



  • 2015 BCM Pilot Award from the Caroline Wiess Law Fund for Research in Molecular Medicine

($30K/yr - 1 year)


  • 2015 AASLD Jan Albrecht Clinical and Translational Research Award in Liver Disease

($75K/yr - 2 years)


  • NIH K23 Training Grant

($150K/yr - 5 years)

  • TCH GI Pilot Grant

($15K/yr - 1 year)


  • Simple Blood Test Developed to Screen for Life Threatening Liver Disease

click on pdf for NEJM article (Aug. 11, 2016)

  • P2X3 purinergic receptor overexpression is associated with poor recurrence-free survival in hepatocellular carcinoma patients

click on pdf for Oncotarget article (December 2015)

  • P2Y2 purinergic receptor activation is essential for efficient hepatocyte proliferation in response to partial hepatectomy

click on pdf for Am J Physiol Gastrointest Liver Physiol article (December 2014)​​

  • Cardiomyopathy reverses with recovery of liver injury, cholestasis and cholanemia in mouse model of biliary fibrosis

click on pdf for Liver International article (​April 2015)

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